24 papers
A 2021–2022 survey of 276 primary care clinicians reveals that while they are motivated to improve obesity care as GLP-1 treatments emerge, they face significant gaps in competence and a lack of organizational and peer support necessary to deliver comprehensive management.
This paper proposes that monitoring serial serum creatinine levels relative to an individual's historical maximum is a more reliable and practical method than estimated GFR equations for detecting early glomerular filtration rate decline above 60 mL/min, enabling earlier intervention before chronic kidney disease stage 3.
Using a discrete choice experiment with 698 participants, this study reveals significant heterogeneity in referral preferences among women at high risk for postpartum depression, identifying that convenience factors like cost and waiting time, alongside personal characteristics, are key drivers for uptake and highlighting the need for flexible, personalized referral programs.
This systematic review and meta-analysis of 15 randomized controlled trials and 8 observational studies concludes that while repeated PSA-based screening for men aged 55–69 likely reduces prostate cancer mortality and metastasis at the cost of significant overdiagnosis and false positives, adding MRI to the screening pathway effectively reduces false positives and overdiagnosis without compromising the detection of clinically significant cancers, though long-term mortality benefits of the MRI strategy remain unproven.
This paper outlines the protocol for a multi-method, Type-2 hybrid effectiveness-implementation study utilizing the RE-AIM framework to evaluate the clinical, organizational, and implementation outcomes of the RIAP interprofessional home care model in Geneva compared to usual care.
This retrospective study of a rural Pacific Northwest clinic found that longer travel times significantly increase in-person appointment cancellations while driving higher telemedicine utilization, which maintains consistent adherence rates across all distance groups, thereby highlighting telehealth as an effective solution for geographic barriers to care.
A prospective before-and-after study in south-west Ghana demonstrates that integrating skin disease care into routine primary health services significantly increased service uptake, particularly in rural areas and among school-age children, yet revealed persistent gaps in access for high-risk groups like males and preschoolers alongside residual catastrophic costs driven by pre-facility expenses.
This systematic review synthesizes evidence from 85 studies to conclude that low-dose CT screening for lung cancer in adults aged 50–74 with significant smoking history reduces lung-cancer mortality but causes substantial harms like overdiagnosis and false positives, resulting in a net benefit that a majority of informed patients likely find acceptable.
This scoping review protocol outlines a systematic plan to map and analyze the fragmented evaluation domains and measurement approaches for China's Family Doctor Contract Services, aiming to establish a consensus-based evidence base for future assessments and core outcome set development.
This consensus study involving UK primary care practitioners and people of reproductive age identified four priority topic areas—patient knowledge, ideas and concerns, health conditions, and health behaviors—to guide structured, opportunistic preconception care discussions in general practice.
This prospective cohort study demonstrates that GP-led removal of patients from end-of-life registers via a systematic digital review process is safe, identifies a distinct group with significantly better survival outcomes, and supports the integration of such digital systems into routine practice and national guidance.
A 2024 survey of 233 Italian general practitioners reveals that while most possess adequate knowledge and recognize their pivotal role in prescribing dietary supplements, a significant majority feel they lack sufficient training on the subject.
Despite high motivation, Dutch general practitioners infrequently initiate conversations about childhood overweight primarily due to practical barriers and internal processes like lack of habituation and negative outcome expectancies, suggesting that interventions should focus on strengthening habit formation and reshaping these cognitive and emotional factors to improve implementation.
This study reveals that while policy advocates for personalized, conversation-based dementia care planning in primary care, inconsistent implementation, time pressures, and fragmented systems hinder effective communication, highlighting the need for clearer roles, formal integration, and targeted training for the wider workforce to bridge the gap between policy ambitions and everyday practice.
This large cohort study of 5 million patients in England found that while overall cancer incidence following abnormal platelet or CRP tests was highest among White patients and similar diagnostic odds ratios were observed across ethnic groups, Black patients exhibited significantly higher diagnostic odds ratios for colorectal cancer specifically, highlighting the critical need for ethnically diverse cohorts to prevent widening healthcare inequalities.
This study demonstrates that manual blood pressure measurements systematically underestimate both blood pressure levels and the associated risk of incident stroke compared to automated devices, potentially leading to inadequate hypertension management.
This study demonstrates that time-domain diffuse correlation spectroscopy (TD-DCS) enables noninvasive, depth-resolved monitoring of cerebral blood flow and low-frequency oscillations, revealing distinct neurovascular dynamics and attenuated task-evoked responses in patients with disorders of consciousness compared to healthy controls.
This prospective feasibility study demonstrates that AI-enabled digital stethoscopes are a practical and effective tool for detecting atrial fibrillation, heart failure, and valvular heart disease in routine general practice, achieving high rates of analyzable recordings with minimal workflow disruption.
A 2024 analysis of the Mount Sinai Health System reveals that despite higher cessation treatment rates for smokers with asthma or COPD compared to those without, only a minority (ranging from 9.9% to 32.6%) received counseling or pharmacotherapy, highlighting a critical gap in care that necessitates system-wide quality improvement.
This UK cohort study reveals that while recurrent sore throat in adults is relatively uncommon, current tonsillectomy practices are poorly aligned with disease burden and exhibit significant socioeconomic inequities, highlighting a need for better identification of high-risk patients and more timely surgical intervention.